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COVID-19 General

Prof Sow and CVD-Mali receive dual honours!

We are extremely pleased to announce that CVD-Mali’s Director General, Professor Samba Sow, has today been honoured both by the Government of Mali and the prestigious National Academy of Medicine (USA) for work in public health and emergency preparedness.

In a ceremony in Bamako today, Prof Sow was made a Commander of the National Order of Mali.

Prime Minister and Head of the National Order of Mali, Choguel Kokalla Maïga, presents Professor Sow with his award

It was also announced that Prof Sow has been elected to the United States’ National Academy of Medicine,

for groundbreaking vaccine field studies … pioneering studies of disease burden and etiology … and leadership in control of emerging infections (Ebola, COVID-19) in Mali and West Africa.

All at CVD-Mali congratulate him warmly – and Professor Sow in turn is proud to accept both awards on behalf of the dedicated and devoted CVD-Mali family in its entirety.

Félicitations!

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COVID-19 General

Watch: Professor Samba Sow addresses WHO press conference

On Wednesday 11 August 2021, Professor Samba Sow, Director General of CVD-Mali, had the pleasure of addressing the WHO’s press conference to introduce the global Solidarity PLUS trial.

Solidarity PLUS is a new, large-scale study to trial new therapeutics to combat COVID-19 and prevent deaths in patients hospitalized and suffering severe cases of the disease.

You can read more about the Solidarity PLUS trial here.

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COVID-19 General

CVD-Mali joins global WHO Solidarity trial

CVD-Mali and the Malian government are delighted to be taking part in WHO’s global trial of new therapeutic treatments for COVID-19.

The Solidarity PLUS trial for promising drugs will be conducted in 52 countries worldwide and is an unprecedented global collaboration for COVID-19 research and development.

The Solidarity therapeutics trial will recruit patients in hospital with COVID-19 in order to test three new drugs.

The therapies were selected by an independent expert panel and have the potential to reduce mortality rates as a result of COVID-19. The three treatments – artesunate, imatinib and infliximab – are established treatments for other diseases. Artesunate is prescribed for severe malaria, imatinib is used to treat certain cancers, and infliximab is often used to treat conditions like Crohn’s Disease and rheumatoid arthritis.

All trial drugs were donated by the manufacturers.

Reacting to the news that Mali would play a central role in the Solidarity PLUS trial, Prof Samba Sow said, “Trials such as the Solidarity PLUS therapeutics trial by WHO are critical.

This increased capacity will ensure we are well placed in Africa to carry on developing the drugs and vaccines that are so necessary – now and in the future.

Prof Samba Sow

“In my career, in vaccine development and research, I have seen the capacity of African researchers and they have a contribution to make now more than ever in solving this puzzle for Africa and the world.

“I am very grateful to WHO and other partners for seeing this opportunity to build capacity and for investment to do so. This increased capacity will ensure we are well placed in Africa to carry on developing the drugs and vaccines that are so necessary – now and in the future.”

The Solidarity PLUS trial is one of the biggest ever global collaborations of its kind, confirming what Prof Sow and the other WHO Special Envoys have long been saying – namely that until everyone is safe from disease, and Covid-19 in particular, no one is.

“In the fight against infectious diseases, a country – even a continent – cannot succeed alone. We will only succeed if we stand and work together,” Professor Sow said.

Click here to watch Prof Sow address the press conference introducing the WHO Solidarity PLUS therapeutics trial, introduced by WHO Director General, Dr Tedros Adhanom Ghebreyesus.

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COVID-19

WHO Special Envoys on Covid-19 advocate for vaccine equity

Professor Samba Sow and the other WHO Special Envoys on COVID-19 recently published an important call for vaccine equity in a number of leading global publications.

Their analysis is available in French, Arabic, Spanish and other languages and can be read in English on the website of The Guardian newspaper here.

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General

In praise of vaccines!

For our team here at CVD-Mali, World Immunization Week is always a notable event on the calendar.

As the Center for Vaccine Development in Mali, our core work has always revolved around the development, trial and implementation of safe and effective vaccines, in Mali primarily but also in the wider West African region.

This year’s World Immunization Week takes place in a more charged context than usual. The whole world, it seems, is talking about vaccines and vaccination.

Unprecedented achievement

In a recent blogpost, we discussed the many challenges associated with the brand new Covid-19 vaccines that have become available, in record time, and as a result of unprecedented scientific achievement.

We made a plea for equitable distribution of these vaccines because immunity against COVID-19 for all, in all countries around the world, is our best hope of putting an end to a global pandemic.

Prof Sow receiving a first dose of COVID-19 vaccine
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General

Working together for better health and fairer societies

At CVD-Mali we are very fortunate to be working at the moment on many different health-related projects. These include vaccine development trials, a leprosy treatment trial, maternal and child health trials as well as ongoing work on surveillance and analysis of COVID-19 in Malian communities. As always, we carry out this work in conjunction with a great many partners and funders and I would like to express my gratitude to them here, not only on behalf of my own institution, CVD-Mali, and the Ministry of Health of Mali, but on behalf of my country and its communities.

Being engaged in such a wide range of projects means that I spend much of my time in the field with my compatriots. On all these visits, it is my great privilege to be invited into people’s villages and daily lives. We talk and laugh, discuss and debate. I am honoured with confidences. Each conversation is above all else, however, an opportunity to learn about the concerns, beliefs, fears and hopes that guide the lives of people in our wonderful communities.

What I hear most often is the expression of a simple, human hope. That their children be able to grow up in good health, peace and prosperity.

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COVID-19 General

Plea for equitable vaccination!

The COVID-19 pandemic in Africa has arrived at a critical point. We are seeing increases in deaths and overwhelmed health systems, in countries that often lack the infrastructure to properly record cases and respond.

I see on the ground the toll all this is taking – on communities, on health workers and on vulnerable populations. West Africa is also dealing with more than one epidemic; as well as COVID-19, we have an ongoing security epidemic and the threat of another Ebola epidemic. COVID-19 has left us exposed and that increases the chances of other health threats snowballing and costing us at least a decade or more of progress.

But there are green shoots of hope. Not the least of which is the incredible efficiency with which the COVID-19 vaccines were developed. These are incredible and inspiring achievements, and a lesson in global collaboration. But this spirit of collaboration is still needed as we move now to the crucial vaccine roll-out.

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COVID-19 General

Reflections on 2020

There has not been much time for reflection this year, it has been a year of crisis and action. However, as well as carrying out our work, it is important too to take some time to pause and reflect.

COVID-19 has affected the world in ways we could never have predicted, and it has been a challenge to us all, whoever and wherever we are.

If there was ever a clear sign of the need to move towards global equity, it is COVID-19

Prof Samba Sow

It has not affected us all equally, however – we are not all in the same boat, as they say. We may all be buffeted by the same great waves of this disease, but we have very different boats in which to try and navigate them. Some have yachts, some dinghies, while some are clinging on to a piece of driftwood. If there was ever a clear sign of the need to move towards global equity, it is COVID-19. Poverty exacerbates COVID-19 and COVID-19 is going to exacerbate poverty. It is estimated that the pandemic will push an additional 88 – 115 million people into extreme poverty this year, with the total rising to as many as 150 million people by 2021, depending on the severity of economic contractions. These people will be more vulnerable to further disease. And this must be reflected as vaccine distribution starts.

As a global community, we must resolve to invest in primary health care and the basic principle of health for all

Prof Samba Sow

For many years I have believed that primary health care and universal health coverage are the keys to delivering health for all. COVID-19 has only strengthened that belief – primary health care is the only way to ensure all our communities have access to routine and lifesaving healthcare. Without strong primary health care, there is no way to overcome this pandemic, to deliver vaccines, to overcome dangerous anti-science and anti-medical opinions, and to build better systems for all. It really is as simple as that. As a global community, we must resolve to invest in primary health care and the basic principle of health for all.

This year, we have seen health being used as a political commodity. This time of crisis has battered entire countries and their populations. The right to health is a fundamental tenet of our human rights and of our understanding of life lived in dignity. As we struggle to make sense of the events of this year, that we remember and act on this principle is my one hope.

2020 has been a uniquely difficult year – but there has also been cause for celebration. The unity and solidarity shown, under WHO’s leadership, in the development of tests, vaccines and treatments for COVID-19 has been inspirational. It has clearly shown how much stronger we are when we act together.

The new year promises to be every bit as challenging as 2020. That makes it more important than ever that we rest, with family and loved ones, over this holiday season, that we may face whatever 2021 has in store refreshed and with renewed strength and unity.

With that, I wish you all, partners, friends and colleagues, a safe, happy and healthy holiday season.

Samba O Sow, Director General, CVD-Mali

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General Lakana Santé

The wisdom of the field

I have spent a large part of my time during the last three months in the field, in various parts of rural Mali, trying to ensure that CVD-Mali’s large-scale trials are able to get up and running.

I have also been working on our ongoing COVID-19 research projects and, of course, training and developing the skills of a whole host of field workers, whose expertise and knowledge are crucial to every one of these projects.

It has been a challenging time – there is so much to do and working in the shadow of the COVID-19 pandemic brings with it an array of problems beyond those we might ordinarily encounter. We have done all that we can to ensure that all our co-workers and study subjects are able to take part in CVD-Mali’s vital healthcare projects without compromising their own health.

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Lakana

Lakana commences in Kita!

On Thursday, 15 October 2020, CVD-Mali gave the first doses of Lakana study medicine to young participants in Kita.

The Lakana trial, which is being carried out with funding from the Bill & Melinda Gates Foundation, aims to assess the impact azithromycin has on mortality rates in children aged 1-11 months.

The CVD-Mali team have been working tirelessly for many months to make sure that this vitally-important trial can take place and, at last, the first children have been enrolled, and the first doses swallowed !

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Administering the very first dose of Lakana study medicine …